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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM54
All Species:
7.58
Human Site:
S216
Identified Species:
20.83
UniProt:
Q969K7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969K7
NP_277039.1
222
23772
S216
R
D
L
L
S
C
T
S
S
E
P
L
T
L
_
Chimpanzee
Pan troglodytes
XP_001157702
242
25361
D224
R
D
W
L
C
C
K
D
A
D
R
P
G
A
E
Rhesus Macaque
Macaca mulatta
XP_001097995
240
25587
S214
E
E
M
I
E
L
E
S
P
K
H
K
R
Q
E
Dog
Lupus familis
XP_854589
268
28613
S262
R
D
L
L
S
C
T
S
S
E
P
L
T
L
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7S1
219
23408
Rat
Rattus norvegicus
Q494T4
216
23309
D210
P
E
P
L
D
G
H
D
L
L
S
C
T
S
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508828
215
23362
P209
P
S
L
Q
T
S
T
P
A
A
P
L
Q
P
_
Chicken
Gallus gallus
XP_419994
226
23376
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956641
240
26403
T231
H
D
L
I
D
K
D
T
V
R
V
E
T
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33
32.5
75
N.A.
74.7
74.7
N.A.
65.7
35.8
N.A.
31.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.6
51.2
77.9
N.A.
85.5
87.8
N.A.
78.3
55.3
N.A.
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
6.6
100
N.A.
0
14.2
N.A.
28.5
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
33.3
100
N.A.
0
21.4
N.A.
42.8
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
23
12
0
0
0
12
0
% A
% Cys:
0
0
0
0
12
34
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
45
0
0
23
0
12
23
0
12
0
0
0
0
12
% D
% Glu:
12
23
0
0
12
0
12
0
0
23
0
12
0
0
23
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% G
% His:
12
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
12
0
0
12
0
12
0
0
0
% K
% Leu:
0
0
45
45
0
12
0
0
12
12
0
34
0
23
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
23
0
12
0
0
0
0
12
12
0
34
12
0
12
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
12
12
0
% Q
% Arg:
34
0
0
0
0
0
0
0
0
12
12
0
12
0
0
% R
% Ser:
0
12
0
0
23
12
0
34
23
0
12
0
0
23
0
% S
% Thr:
0
0
0
0
12
0
34
12
0
0
0
0
45
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% _